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What is the recommended first dose of lidocaine during ACLS?

1-1.5 mg/kg

In ACLS, lidocaine is used as an IV antiarrhythmic for ventricular arrhythmias, and the first dose should be 1-1.5 mg/kg given rapidly as a bolus. This dose quickly achieves therapeutic levels to help terminate or suppress the arrhythmia during CPR. If needed, a second dose of 0.5-0.75 mg/kg can be given every 5-10 minutes, up to a total max of 3 mg/kg. Monitor for signs of lidocaine toxicity, and use lidocaine as an option when amiodarone isn’t available or the rhythm remains refractory.

0.5-1 mg/kg

2-3 mg/kg

0.1-0.3 mg/kg

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